Case Report| Volume 26, ISSUE 3, P204-207, September 2022

Mycosis fungoides: A rare cause of giant cardiac mass


      Mycosis fungoides is the most common cutaneous T-cell lymphoma. Although myocardial infiltration is frequent in advanced stages, symptomatic cardiac involvement is rare. We report an unusual case of rapidly progressing acute heart failure due to cardiac affection by mycosis fungoides manifested as an intracavitary mass in the right atrium. The patient received cytoreductive surgery and adjuvant radiotherapy, presenting an excellent cardiovascular outcome during follow-up.

      Learning objectives

      • Recognize mycosis fungoides as a potential cause of cardiac mass due to its visceral progression.
      • Note the role of cytoreductive surgery with adjuvant radiotherapy in order to relieve heart failure symptoms and improve the prognosis of the disease in the exceptional case of mycosis fungoides presenting as an isolated cardiac mass.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Cardiology Cases
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • O’Mahony D.
        • Peikarz R.L.
        • Bandettini W.P.
        • Arai A.E.
        • Wilson W.H.
        • Bates S.E.
        Cardiac involvement with lymphoma: a review of the literature.
        Clin Lymphoma Myeloma. 2008; 8: 249-252
        • Tabata T.
        • Kiuchi K.
        • Nagamatsu Y.
        • Shinkura Y.
        • Uzu K.
        • Ooka J.
        • et al.
        A case of acute heart failure due to myocardial infiltration of mycosis fungoides.
        J Cardiol Cases. 2018; 18: 95-98
        • Tyebally S.
        • Chen D.
        • Bhattacharyya S.
        • Mughrabi A.
        • Hussain Z.
        • Manisty C.
        • et al.
        Cardiac tumors: JACC CardioOncology state-of-the-art review.
        JACC CardioOncology. 2020; 2: 293-311
        • Cresti A.
        • Chiavarelli M.
        • Glauber M.
        • Tanganelli P.
        • Scalese M.
        • Cesareo F.
        • et al.
        Incidence rate of primary cardiac tumors: a 14-year population study.
        J Cardiovasc Med. 2016; 17: 37-43
        • Wu H.M.
        • Chen Y.
        • Xiao Z.B.
        • Zhang F.
        • Wu M.
        • Zhu X.L.
        • et al.
        Clinical and pathological characteristics of cardiac tumors: analyses of 689 cases at a single medical center.
        Chin J Pathol. 2019; 48: 293-297
        • Klatt E.C.
        • Heitz D.R.
        Cardiac metastases.
        Cancer. 1990; 65: 1456-1459
        • Servitje O.
        • Limón A.
        • Blanco A.
        • Carmona M.
        • Serrano T.
        • Romagosa V.
        • et al.
        Cardiac involvement and molecular staging in a fatal case of mycosis fungoides.
        Br J Dermatol. 1999; 141: 531-535
        • Carrilho-Ferreira P.
        • Ferreira M.
        • Ferreira C.
        • Correia M.J.
        • Nunes A.
        • Bras L.
        Ventricular tachycardia revealing cardiac infiltration by mycosis fungoides.
        Rev Port Cardiol. 2014; 33: 481-482
        • Bahali A.G.
        • Su O.
        • Cengiz F.P.
        • Emiroğlu N.
        • Ozkaya D.B.
        • Onsun N.
        Prognostic factors of patients with mycosis fungoides.
        Postepy Dermatol Alergol. 2020; 37: 796-799
        • Basso C.
        • Rizzo S.
        • Valente M.
        • Thiene G.
        Cardiac masses and tumours.
        Heart. 2016; 102: 1230-1245