Abstract
Cardiac calcified amorphous tumors are rare non-neoplastic intracavitary masses. Herein,
we report a case of a 75-year-old woman who presented with dyspnea on exertion and
multiple cerebral infarctions 3 months prior. Transthoracic echocardiography showed
severe mitral regurgitation from the posterior mitral leaflet with valve perforation
and severe mitral annular calcification. In addition, we observed a 13 mm mobile high
echogenic mass, suggesting healed infective endocarditis. The mass was successfully
resected, and the mitral valve was replaced with a bovine pericardial patch for the
decalcified annulus. Histopathological examination confirmed cardiac calcified amorphous
tumor; the postoperative course was uneventful. Mitral valve replacement and annulus
patch repair effectively prevented postoperative recurrent systemic embolization.
<Learning objective: Calcified amorphous tumor (CAT) is a risk factor for systemic embolism. Cardiac CAT
destroying the mitral valve tissue and causing mitral valvular disease have been scarcely
reported. We present a case of cardiac CAT with mitral valve perforation and suspected
systemic embolization, treated successfully through mitral valve replacement and calcified
lesion coverage by surgical resection and patch repair.>
Keywords
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References
- Calcified amorphous tumor of the heart (cardiac CAT).Hum Pathol. 1997; 28: 601-606
- Cardiac calcified amorphous tumor: a systematic review of the literature.Int J Cardiol Heart Vasc. 2015; 7: 1-5
- A calcified amorphous tumor causing mitral valve perforation and ruptured chordae tendineae.Jpn J Cardiovasc Surg. 2019; 48: 259-262
- Spontaneous mitral valve perforation associated with mitral annular calcification-related calcified amorphous tumor assessed by three-dimensional transesophageal echocardiography.J Med Ultrason. 2020; 47: 481-482
- Left ventricular lipomatous hamartoma mimicking a calcified amorphous tumor.Circulation. 2016; 133: e408-e410
- Anterior mitral valve perforation in the absence of acute infection: diagnosis by two-dimensional and three-dimensional transesophageal echocardiography.Echocardiography. 2017; 34: 1953-1955
- Recurrent cardiac calcific amorphous tumor: the CAT had a kitten.Cardiovasc Pathol. 2007; 16: 115-118
- Swinging calcified amorphous tumors with related mitral annular calcification.Ann Thorac Surg. 2016; 101: e103-e105
Article info
Publication history
Published online: January 03, 2022
Accepted:
November 17,
2021
Received in revised form:
October 25,
2021
Received:
August 14,
2021
Identification
Copyright
© 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.