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Case Report| Volume 25, ISSUE 5, P297-299, May 2022

Cardiac calcified amorphous tumor with mitral valve perforation: A case report

Published:January 03, 2022DOI:https://doi.org/10.1016/j.jccase.2021.11.010

      Abstract

      Cardiac calcified amorphous tumors are rare non-neoplastic intracavitary masses. Herein, we report a case of a 75-year-old woman who presented with dyspnea on exertion and multiple cerebral infarctions 3 months prior. Transthoracic echocardiography showed severe mitral regurgitation from the posterior mitral leaflet with valve perforation and severe mitral annular calcification. In addition, we observed a 13 mm mobile high echogenic mass, suggesting healed infective endocarditis. The mass was successfully resected, and the mitral valve was replaced with a bovine pericardial patch for the decalcified annulus. Histopathological examination confirmed cardiac calcified amorphous tumor; the postoperative course was uneventful. Mitral valve replacement and annulus patch repair effectively prevented postoperative recurrent systemic embolization.
      <Learning objective: Calcified amorphous tumor (CAT) is a risk factor for systemic embolism. Cardiac CAT destroying the mitral valve tissue and causing mitral valvular disease have been scarcely reported. We present a case of cardiac CAT with mitral valve perforation and suspected systemic embolization, treated successfully through mitral valve replacement and calcified lesion coverage by surgical resection and patch repair.>

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      References

        • Reynolds C.
        • Tazelaar H.D.
        • Edwards WD.
        Calcified amorphous tumor of the heart (cardiac CAT).
        Hum Pathol. 1997; 28: 601-606
        • de Hemptinne Q.
        • de Cannière D.
        • Vandenbossche J.L.
        • Unger P.
        Cardiac calcified amorphous tumor: a systematic review of the literature.
        Int J Cardiol Heart Vasc. 2015; 7: 1-5
        • Kinugasa Y.
        • Teshima H.
        • Inoue Y.
        • Tai R.
        • Sato M.
        • Ikebuchi M.
        • Irie H.
        A calcified amorphous tumor causing mitral valve perforation and ruptured chordae tendineae.
        Jpn J Cardiovasc Surg. 2019; 48: 259-262
        • Haruki N.
        • Sumi N.
        • Kobara S.
        • Tsujimoto D.
        • Inoue Y.
        • Saito Y.
        • Shirota K.
        Spontaneous mitral valve perforation associated with mitral annular calcification-related calcified amorphous tumor assessed by three-dimensional transesophageal echocardiography.
        J Med Ultrason. 2020; 47: 481-482
        • Torii Y.
        • Yamada H.
        • Matsukuma S.
        • Nishio S.
        • Kusunose K.
        • Abe M.
        • Sata M.
        Left ventricular lipomatous hamartoma mimicking a calcified amorphous tumor.
        Circulation. 2016; 133: e408-e410
        • Mashicharan M.
        • Cowburn P.J.
        • Livesey S.A.
        • Shah BN.
        Anterior mitral valve perforation in the absence of acute infection: diagnosis by two-dimensional and three-dimensional transesophageal echocardiography.
        Echocardiography. 2017; 34: 1953-1955
        • Fealey M.E.
        • Edwards W.D.
        • Reynolds C.A.
        • Pellikka P.A.
        • Dearani JA.
        Recurrent cardiac calcific amorphous tumor: the CAT had a kitten.
        Cardiovasc Pathol. 2007; 16: 115-118
        • Matsukuma S.
        • Eishi K.
        • Tanigawa K.
        • Miura T.
        • Matsumaru I.
        • Hisatomi K.
        • Tsuneto A.
        Swinging calcified amorphous tumors with related mitral annular calcification.
        Ann Thorac Surg. 2016; 101: e103-e105