Isolated extreme right ventricular hypertrophy: A case report

Published:November 17, 2021DOI:https://doi.org/10.1016/j.jccase.2021.10.002

      Abstract

      Hypertrophic cardiomyopathy (HCM) can involve the right ventricle (RV), although RV hypertrophy usually exists with left ventricular (LV) hypertrophy and the severity of hypertrophy is milder in the RV than in the LV. We report a case of isolated extreme RV hypertrophy with a maximum RV wall thickness of 40 mm. A 72-year-old man presented with an abnormal electrocardiogram and isolated hypertrophy of the RV apex was found on echocardiography. A diagnosis of HCM was made based on myocardial features on multiple imaging modalities such as the similar myocardial characteristics to LV hypertrophy and systolic thickening. The isolated hypertrophy of the RV apex exhibited partial calcification, which was surrounded by hypoperfused areas of the myocardium on multidetector computed tomography.

      Keywords

      To read this article in full you will need to make a payment

      References

        • Marian A.J.
        • Braunwald E.
        Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy.
        Circ Res. 2017; 121: 749-770
        • Maron M.S.
        • Hauser T.H.
        • Dubrow E.
        • Horst T.A.
        • Kissinger K.V.
        • Udelson J.E.
        • Manning W.J.
        Right ventricular involvement in hypertrophic cardiomyopathy.
        Am J Cardiol. 2007; 100: 1293-1298
        • Guo X.
        • Fan C.
        • Tian L.
        • Liu Y.
        • Wang H.
        • Zhao S.
        • Duan F.
        • Zhang X.
        • Zhao X.
        • Wang F.
        • Zhu H.
        • Lin A.
        • Wu X.
        • Li Y.
        The clinical features, outcomes and genetic characteristics of hypertrophic cardiomyopathy patients with severe right ventricular hypertrophy.
        PLoS One. 2017; 12e0174118
        • Keramida K.
        • Lazaros G.
        • Nihoyannopoulos P.
        Right ventricular involvement in hypertrophic cardiomyopathy: patterns and implications.
        Hellenic J Cardiol. 2020; 61: 3-8
        • Nakamura T.
        • Sawada T.
        • Kuribayashi T.
        • Harada Y.
        • Matsumuro A.
        • Narihara R.
        • Azuma A.
        • Sugihara H.
        • Kohno Y.
        • Katsume H.
        • Nakagawa M.
        • Kunishige H.
        Ultrasonic tissue characterization in hypertrophic cardiomyopathy: analysis of three-layered appearance of the ventricular septum by apical approach.
        Kokyu To Junkan. 1992; 40 (In Japanese): 891-896
        • Li M.
        • Zhang L.
        • Zhang Z.
        • Wang S.
        • Dong N.
        • Wang G.
        • Xie M.
        Isolated severe right ventricular hypertrophic cardiomyopathy.
        Ann Thorac Surg. 2019; 10: e23-e25
        • Chatterjee D.
        • Narayan P.
        Idiopathic isolated right ventricular apical hypertrophy.
        Acta Cardiol Sin. 2018; 34: 288-290
        • Guo X.
        • Fan C.
        • Wang H.
        • Zhao S.
        • Duan F.
        • Wang Z.
        • Yan L.
        • Yang Y.
        • An S.
        • Li Y.
        The prevalence and long-term outcomes of extreme right versus extreme left ventricular hypertrophic cardiomyopathy.
        Cardiology. 2016; 133: 35-43
        • Kaimoto S.
        • Kawasaki T.
        • Yamano M.
        • Miki S.
        • Kamitani T.
        • Sugihara H.
        Intramyocardial calcification in a patient with apical hypertrophic cardiomyopathy.
        Intern Med. 2012; 51: 1523-1526
        • Muthukumar L.
        • Jan M.F.
        • Whitnah J.
        • Tajik A.J.
        Coexistence of apical hypertrophic cardiomyopathy and endomyocardial fibrosis with calcification: diagnosis using multimodality imaging.
        ESC Heart Fail. 2016; 3: 278-281