Acute mitral regurgitation after non-ischemic papillary muscle rupture: A case report

Published:November 15, 2021DOI:


      Papillary muscle rupture (PMR) is a life-threatening cardiac emergency that is generally associated with inadequate myocardial perfusion after acute myocardial infarction. Nonischemic spontaneous PMR occurs less frequently and is mostly caused by myocarditis, infections, or trauma. We report a patient with spontaneous PMR resulting in severe mitral regurgitation with refractory heart failure showing no specific causes but deterioration of the mitral leaflet and papillary muscle. The integration of pathologic and echocardiographic findings describes the details of the disease.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic and Personal
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Cardiology Cases
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Roberts W.C.
        • Cohen L.S.
        Left ventricular papillary muscles: description of the normal and a survey of conditions causing them to be abnormal.
        Circulation. 1972; 46: 138-154
        • Gouda P.
        • Weilovitch L.
        • Kanani R.
        • Har B.
        Case report and review of nonischemic spontaneous papillary muscle rupture reports between 2000 and 2015.
        Echocardiography. 2017; 34: 786-790
        • Roberts W.C.
        • Vowels T.J.
        • Ko J.M.
        • Hebeler R.F.
        Gross and histological features of excised portions of posterior mitral leaflet in patients having operative repair of mitral valve prolapse and comments on the concept of missing(=ruptured) chordas.
        J Am Coll Cardiol. 2014; 63: 1667-1674
        • Barlow J.B.
        • Pocock W.A.
        Billowing, floppy, prolapsed or flail mitral valves?.
        J Am Coll Cardiol. 1985; 55: 501-502